Pre_GI: SWBIT SVG BLASTP

Query: NC_008343:823093 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.

Subject: NC_014804:803510 Thermococcus barophilus MP chromosome, complete genome

Lineage: Thermococcus barophilus; Thermococcus; Thermococcaceae; Thermococcales; Euryarchaeota; Archaea

General Information: This organism was collected from the chimney wall of a Mid-Atlantic hydrothermal vent known as "Snakebite", at a depth of 3550 m. It was isolated under in situ pressure. True barophilic and hyperthermophilic archaeon strain.