Query: NC_008343:61191 Granulibacter bethesdensis CGDNIH1, complete genome Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.
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General Information: Isolated from freshwater sulfide-rich mud of a waterway near Kameno river, Wakayama, in Japan. This organism is a sulfate-reducing delta proteobacterium which synthesizes intracellular magnetite particles. Desulfovibrio magneticus produces irregular, membrane-bound magnetite particles, unlike other magnetite-producing bacteria which contain crystalline magnetite in the cytoplasm. Desulfovibrio magneticus does not migrate along a magnetic field but swims randomly.