Pre_GI: SWBIT SVG BLASTP

Query: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.

Subject: NC_003364:1081846 Pyrobaculum aerophilum str. IM2, complete genome

Lineage: Pyrobaculum aerophilum; Pyrobaculum; Thermoproteaceae; Thermoproteales; Crenarchaeota; Archaea

General Information: This organism was isolated from a boiling marine water hole in Maronti Beach, Ischia, Italy. It grows optimally a 100ºC and pH 7.0. Growth can occur at temperatures between 74 and 104 ºC. Nitrate-reducing hyperthermophilic archeon. This organism is a facultatively anaerobic, nitrate-reducing hyperthermophilic archaeon. It is able to grow both aerobically and anaerobically by dissimilatory nitrate reduction.