Pre_GI: SWBIT SVG BLASTP

Query: NC_008343:2020785 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.

Subject: NC_015185:485866 Desulfurobacterium thermolithotrophum DSM 11699 chromosome,

Lineage: Desulfurobacterium thermolithotrophum; Desulfurobacterium; Desulfurobacteriaceae; Desulfurobacteriales; Aquificae; Bacteria

General Information: Environment: Marine; Isolation: Deep-sea hydrothermal vent chimney; Temp: Thermophile; Temp: 70C; Country: Atlantic Ocean: Mid-Atlantic Ridge. This thermophilic, anaerobic, strictly autotrophic, sulfur-reducing bacteriumwas isolated from a deep-sea hydrothermal chimney sample collected at the mid-Atlantic ridge.