Pre_GI: SWBIT SVG BLASTP

Query: NC_008343:2020785 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.

Subject: NC_012793:2122036 Geobacillus sp. WCH70, complete genome

Lineage: Geobacillus; Geobacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Temp: Thermophile. Recent rDNA analysis and DNA-DNA hybridization studies using spore-forming thermophilic subsurface isolates from formation waters of oilfields in Russia, Kazakhstan and China provided enough evidence to define the phylogenetically distinct, physiologically and morphologically consistent taxon Geobacillus. Geobacillus species are chemo-organotrophic, obligately thermophilic, neutrophilic, motile, spore-forming, aerobic or facultatively anaerobic Gram-positive bacterium.