Pre_GI: SWBIT SVG BLASTP

Query: NC_008343:2020785 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.

Subject: NC_012489:1874415 Gemmatimonas aurantiaca T-27, complete genome

Lineage: Gemmatimonas aurantiaca; Gemmatimonas; Gemmatimonadaceae; Gemmatimonadales; Gemmatimonadetes; Bacteria

General Information: Gram-negative, rod-shaped aerobe. Polyphosphate accumulating bacterium. This species was isolated from an anaerobic-aerobic sequential batch reactor operated under enhanced biological phosphorus removal conditions for wastewater treatment. The isolation strategy used targeted slowly growing polyphosphate-accumulating bacteria by combining low-speed centrifugations and prolonged incubation on a low-nutrient medium. This is the first isolated species in the Gemmatimonadetes phylum.