Query: NC_008343:2020785 Granulibacter bethesdensis CGDNIH1, complete genome Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.
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General Information: Aeromonas salmonicida subsp. salmonicida A449 was isolated from a brown trout with furunculosis. The agent of furunculosis, a major cause of mortality among salmonid fishes. This bacterium is the causal agent of furunculosis. Although it was discovered nearly 100 years ago, it is not known how the diesase is spread. Furunculosis is temperature sensistive, with acute cases occurring when the water is above 20 degrees C and chronic cases developing at temperatures below 13 degrees C. The acute form of the disease causes the fish to turn a dark color and stop eating.