Query: NC_008340:480399 Alkalilimnicola ehrlichei MLHE-1, complete genome Lineage: Alkalilimnicola ehrlichii; Alkalilimnicola; Ectothiorhodospiraceae; Chromatiales; Proteobacteria; Bacteria General Information: This chemoautotrophic strain was isolated from Mono Lake in California, which contains arsenic and has high pH and salt concentrations. Arsenite-oxidizing bacterium. Alkalilimnicola ehrlichei is capable of growth with arsenite [As(III)] as the electron donor with nitrate as electron acceptor. It may be responsible for production of arsenate [As(V)] in anoxic lake bottom.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.