Query: NC_008309:1851189 Haemophilus somnus 129PT, complete genome Lineage: Histophilus somni; Histophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria General Information: This strain is an asymptomatic carrier strain that was serum-resistant. Causes disease in cattle. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism is a major cause of disease in feedlot cattle. It causes constriction of blood vessels supplying major organs, restricting blood supply which leads to reduced oxygen delivery, and leads to tissue damage and death. The diseases that result are pneumonia, arthritis, myocarditis (inflammation of heart muscle), and reproductive problems resulting in the loss of millions of dollars in animals each year.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This organism is the endosymbiont of the American cockroach, Periplaneta americana. It is a Gram-negative maternally inherited bacteria which lives in specialized cells in the host's abdominal fat body. Phylogenetic analyses for the Blattabacterium-cockroach symbiosis supports the hypothesis of co-evolution between symbionts and hosts dating back to more than 140 million years ago. Cockroaches are omnivorous insects, often subsisting on a nitrogen-poor diet, and Blattabacterium have been hypothesized to participate in uric acid degradation, nitrogen assimilation, and nutrient provisioning. Genome sequencing and metabolic reconstruction shows that Blattabacterium can recycle nitrogen from urea and ammonia, which are uric acid degradation products, into glutamate, using urease and glutamate dehydrogenase, and thus would be able to provide its host with some essential amino acids, vitamins and cofactors. The bacterium relies on asparagine and glutamine supplied by the host; it may be able to make proline from arginine via the urea cycle.