Query: NC_008260:2961291 Alcanivorax borkumensis SK2, complete genome Lineage: Alcanivorax borkumensis; Alcanivorax; Alcanivoracaceae; Oceanospirillales; Proteobacteria; Bacteria General Information: This bacterium was isolated from a seawater sediment sample in the North Sea. The species is able to use Mihagol-S (C14,15-n-alkanes) as a principal carbon source. Using n-alkanes as a sole carbon source causes the strains to produce extracellular and membrane-bound surface-active glucose lipids. Phenotypic analysis showed a restricted nutritional profile, high halotolerance, the absence of fermentative metabolism, and a low G+C content. This, in combination with a 16S phylogenetic study, allowed the placing of this organism into a new genus.
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General Information: This strain was isolated from infant feces. Normal human gut flora. Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. This organism is found in adult humans and formula fed infants as a normal component of gut flora.