Query: NC_008212:1759535 Haloquadratum walsbyi DSM 16790, complete genome
Lineage: Haloquadratum walsbyi; Haloquadratum; Halobacteriaceae; Halobacteriales; Euryarchaeota; Archaea
General Information: A uniquely square archaeon. This hyperhalophile is of specific interest because of its unique square shape and extraordinarily large size (40m x 40m). Its culture conditions were optimized in 2004.
Subject: NC_008343:2020785 Granulibacter bethesdensis CGDNIH1, complete genome
Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.