Query: NC_008095:6323456 Myxococcus xanthus DK 1622, complete genome Lineage: Myxococcus xanthus; Myxococcus; Myxococcaceae; Myxococcales; Proteobacteria; Bacteria General Information: First isolated from soil in 1941. Bacterium with a multi-stage lifecycle. M.xanthus is a Gram-negative rod-shaped bacterium. This organism undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. This organism is also utilized industrially to produce the anticancer drug epithilone.
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General Information: Environment: Rhizosphere, Host, Rhizosphere-colonizing; Temp: Mesophile. This species is an uncommon but serious source of infection in patients with breathing tubes such as endotracheal or tracheostomy tubes, or with chronically indwelling urinary catheters. Although the organism can colonize the devices without causing an infection, under certain conditions it can cause pneumonia, urinary tract infections, or an infection of the blood. This organism can also cause infection in immunocompromised patients. It has resistance to many commonly used antibiotics and therefore is often difficult to eradicate. Most strains are resistant to co-trimoxazole.