Query: NC_008095:6143738 Myxococcus xanthus DK 1622, complete genome Lineage: Myxococcus xanthus; Myxococcus; Myxococcaceae; Myxococcales; Proteobacteria; Bacteria General Information: First isolated from soil in 1941. Bacterium with a multi-stage lifecycle. M.xanthus is a Gram-negative rod-shaped bacterium. This organism undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. This organism is also utilized industrially to produce the anticancer drug epithilone.
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General Information: This strain was isolated prior to 1985 and belongs to the antiqua biovar. It can ferment rhamnonse and melibiose which is a property usually associated with Yersinia pseudotuberculosis. Strain Angola belongs to a group of atypical Yersinia pestis strains with genotypic similarities that are intermediate between Y. pestis and Y. pseudotuberuclosis strains. Genotypic studies indicate that strain Angola is the oldest Y. pestis strain analyzed to date. It carries three plasmids that are similar to other Y. pestis plasmids but have aberrant sizes. The critical virulence factor, the V antigen, is different than that encoded by typical strains of Y. pestis and there is a deletion that affects the F1 operon. Strain Angola has been shown to be virulent by aerosol in mice.