Query: NC_008095:6143738 Myxococcus xanthus DK 1622, complete genome
Lineage: Myxococcus xanthus; Myxococcus; Myxococcaceae; Myxococcales; Proteobacteria; Bacteria
General Information: First isolated from soil in 1941. Bacterium with a multi-stage lifecycle. M.xanthus is a Gram-negative rod-shaped bacterium. This organism undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. This organism is also utilized industrially to produce the anticancer drug epithilone.
Subject: NC_006155:2084669 Yersinia pseudotuberculosis IP 32953, complete genome
Lineage: Yersinia pseudotuberculosis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This strain is a fully virulent serotype I strain isolated from a human patient. Environmental bacterium that causes gastrointestinal disease. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. This organism was first isolated in 1883 by Malassez and Vignal and is termed pseudotuberculosis since it causes lesions in the lung that are similar to those observed during tuberculosis infection. It is ubiquitous in the environment and is a food and waterborne pathogen that affects animals as well as humans by causing gastroenteritis like Yersinia enterocolitica.