Query: NC_008060:1945597 Burkholderia cenocepacia AU 1054 chromosome 1, complete sequence
Lineage: Burkholderia cenocepacia; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: This organism (AU 1054) was isolated from the blood of a patient with CF. This microbe has three chromosomes. Opportunistic pathogen. This species (genomovar III) is part of the Burkholderia cepacia complex, which consists of 9 closely related species, also known as genomovars. These organisms are commonly found in soil and all are opportunistic pathogens espcially in cystic fibrosis patients.
Subject: NC_000963:110500 Rickettsia prowazekii str. Madrid E, complete genome
Lineage: Rickettsia prowazekii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.