Pre_GI: SWBIT SVG BLASTP

Query: NC_008011:1394777 Lawsonia intracellularis PHE/MN1-00, complete genome

Lineage: Lawsonia intracellularis; Lawsonia; Desulfovibrionaceae; Desulfovibrionales; Proteobacteria; Bacteria

General Information: Lawsonia intracellularis PHE/MN1-00 was isolated from intestinal mucosal lesions in pigs that had proliferative enteropathy (PE). When introduced into health pigs, this organism produced the clinical and histological signs of PE. Causative agent for proliferative enteropathy in swine. This organism causes proliferative enteropathy (ileitis) in swine and other domesticated animals resulting in severe losses each year. This obligate intracellular pathogen infects the mucosa of the lower intestinal tract by initially infecting crypt cells, which are precursors that normally grow and divide in order to replace the epithelial cells. Once infection occurs, the crypt cells are stimulated to grow and divide abnormally, resulting in the proliferative phenotype. In severe cases of the disease the entire bowel can become affected and persist for up to 40 days, greatly affecting the host animal.

Subject: NC_005303:553500 Onion yellows phytoplasma OY-M, complete genome

Lineage: Onion yellows phytoplasma; Phytoplasma; Acholeplasmataceae; Acholeplasmatales; Tenericutes; Bacteria

General Information: This strain (OY-M) is derived from a wild-type disease-causing strain (OY-W; onions yellow disease) which was isolated in Saga Prefecture, Japan, in 1982, and shows mild symptoms and does not cause stunting nor phloem hyperplasia (excessive increase in number of cells). Plant pathogenic bacterium. Phytoplasmas inhabit phloem (food-conducting vascular tissue) sieve elements of plants where they cause a variety of diseases. There is great interest in sequencing these organisms since they are currently unculturable and examination of the genome may lead to methods to deal with the diseases they cause including the development of antimicrobial agents. There is great interest in sequencing these organisms since they are currently unculturable and examination of the genome may lead to methods to deal with the diseases they cause including the development of antimicrobial agents.