Query: NC_007974:1007834 Ralstonia metallidurans CH34 chromosome 2, complete sequence Lineage: Cupriavidus metallidurans; Cupriavidus; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: This strain was first identified in the heavy metal-contaminated sludge of a settling tank in Belgium in the late 1970s. This organism, formerly Ralstonia metallidurans, is capable of growth in the presence of a large number of heavy metals including silver, cadmium, chromium, cobalt, copper, mercury, nickel, lead, thallium, and zinc.
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General Information: This species is associated with infections in cystic fibrosis patients. It is an important opportunistic pathogen, colonizing the lungs and associated with a decrease in long-term survival. A minority of patients with this infection may also develop "cepacia syndrome", which leads to an acute clinical decline which is frequently fatal. This species is a member of the Burkholderia cepacia complex, although it does not appear to spread from patient to patient as do the other members of the group.