Query: NC_007907:2306561 Desulfitobacterium hafniense Y51, complete genome Lineage: Desulfitobacterium hafniense; Desulfitobacterium; Peptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: This strain was isolated from soil contaminated with tetrachloroethene (PCE) in Japan. It can efficiently dehalogenate PCEs via trichloroethene (TCE) to cis-1,2-dichloroethene (cis-1,2-DCE). It can also dehalogenase tetra-, penta-, and hexachloroethanes. Hydrocarbon dehalogenator. This organism can dehalogenate a variety of hydrocarbons and can utilize fumarate, sulfite, and thiosulfate (but not thiousulfate) as terminal electron acceptors. Some important pollutants such as polychlorinated biphenyls (PCBs) may be degraded by this organism.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.