Pre_GI: SWBIT SVG BLASTP

Query: NC_007799:968499 Ehrlichia chaffeensis str. Arkansas, complete genome

Lineage: Ehrlichia chaffeensis; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.

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BLASTP Alignment.txt

Subject: NC_014330:1113145 Brachyspira pilosicoli 95/1000 chromosome, complete genome

Lineage: Brachyspira pilosicoli; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria

General Information: The strain Brachyspira pilosicoli 95/1000 was isolated from a pig. Brachyspira pilosicoli is an anaerobic spirochete that colonizes the large intestine of various species of birds and animals and humans. It attaches to colonic enterocytes in a condition called 'intestinal spirochetosis', characterized by mild colitis, diarrhea and reduced growth.