Pre_GI: SWBIT SVG BLASTP

Query: NC_007799:968499 Ehrlichia chaffeensis str. Arkansas, complete genome

Lineage: Ehrlichia chaffeensis; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.

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Subject: NC_004757:2213806 Nitrosomonas europaea ATCC 19718, complete genome

Lineage: Nitrosomonas europaea; Nitrosomonas; Nitrosomonadaceae; Nitrosomonadales; Proteobacteria; Bacteria

General Information: Ammonia-oxidizing bacterium. This organism is an obligate chemo-lithoautotroph as it only uses ammonia and carbon dioxide and mineral salts for growth, and is an important part of the global biogeochemical nitrogen cycle. It can derive all energy requirements from the oxidation of ammonia to nitrate, driving global nitrogen from the reduced insoluble form to the oxidized and potentially gaseous form (including NO and NO2 which are greenhouse gases). The energy derived from ammonia oxidation is in turn used to drive carbon fixation. This bacterium also provides plants with a readily available form of nitrogen, is important in wastewater treatment, and may be involved in bioremediation of sites contaminated with toxic compounds.