Pre_GI: SWBIT SVG BLASTP

Query: NC_007799:968499 Ehrlichia chaffeensis str. Arkansas, complete genome

Lineage: Ehrlichia chaffeensis; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.

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BLASTP Alignment.txt

Subject: NC_001318:377039 Borrelia burgdorferi B31, complete genome

Lineage: Borrelia burgdorferi; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This organism is the causative agent of Lyme disease, a multisystemic disease that is considered to be the most prevalent tick-born disease in North America and Europe. This organism was isolated from Ixodes scapularis in 1982. The bacterium is a microaerophilic spirochete that contains seven periplasmic flagella per cell end.