Query: NC_007798:586500 Neorickettsia sennetsu str. Miyayama, complete genome Lineage: Neorickettsia sennetsu; Neorickettsia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria General Information: This organism was first described in 1953 in Japan as causing Sennetsu fever. Causes an infectious mononucleosis-like disease. Like other Ehrlichia, this organism is an obligate intracellular pathogen. It can be transmitted from fish flukes (trematodes) to humans, and was one of the first Ehrlichia that was found to cause a human-specific illness.
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General Information: A nematode endosymbiont. This group of bacteria are associated with a variety of invertebrate species, some as pathogens, some in a symbiotic relationship. Typically these organisms are transmitted maternally from mother to daughter transovarially (through the egg) although these bacteria can affect their hosts reproductive capabilities in order to enhance transmission. The net outcome is the increase of hosts carrying the bacteria in the next generation, thereby increasing transmission. This strain naturally infects Brugia malayi, a parasitic filarial nematode that causes lymphatic filariasis, one of the most devastating diseases in humans. The endosymbiont plays important roles in the biology of the nematide host. One of the known such effects are aberrant sex ratios in the host, parthenogenesis and feminization of genetic males, etc.