Query: NC_007712:1954808 Sodalis glossinidius str. 'morsitans', complete genome Lineage: Sodalis glossinidius; Sodalis; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: Sodalis glossinidius is known exclusively in endosymbiosis with tsetse flies. It is maternally transmitted, and is one of the few bacterial endosymbionts of insects that can be cultured successfully in vitro. Genome data reveals a high proportion of pseudogenes in this species, many of which were, in their functional state, involved in defense or transport of carbohydrates and inorganic ions. This suggests a degenerative adaptation to the immunity and restricted nutritional status of the host.
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General Information: Normal oral and gastrointestinal bacterium. This genus contains mostly obligately anaerobic bacilli. Many of the isolates are spindle-shaped, or fusiform. This organism belongs to the normal microflora of the human oral and gastrointestinal tracts. It is a very long and slender spindle-shaped bacillus with sharply pointed ends that is characterized by the ability to invade soft tissues. It acts as a bridge between early and late colonizers of the tooth surface, and exerts synergism with other bacteria in mixed infections. It is most frequently associated with periodontal diseases, as well as with some invasive human infections of the head and neck, chest, lung, liver and abdomen, and some anginas. One of the major amino acid and sugar fermentation pathways in Fusobacterium nucleatum produces butyric and acetic acids.