Query: NC_007517:1561466 Geobacter metallireducens GS-15, complete genome Lineage: Geobacter metallireducens; Geobacter; Geobacteraceae; Desulfuromonadales; Proteobacteria; Bacteria General Information: First isolated from the Potomac river downstream of Washington, DC, USA in 1987. This organism actively moves towards metal attractants such as iron and manganese oxides, which are insoluble, and produces type IV pili for attachment to the insoluble substrates. Common metal-reducing bacterium. This organism, similar to what is observed in Geobacteria sulfurreducens, couples the oxidation of organic molecules to the reduction of iron by using insoluble Fe (III) as an electron acceptor under anaerobic conditions. This bacterium plays an imporant part of the nutrient cycling in aquatic environments. The cell can also use uranium and plutonium, therefore, this organism and may be important for the bioremediation of contaminated waste sites.
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General Information: This strain is a human clinical isolate from a human burn patient. It is infectious in mice, Caenorhabditis elegans, Drosophila melanogaster, and Arabidopsis thaliana. Opportunistic pathogen. Bacteria belonging to the Pseudomonas group are common inhabitants of soil and water and can also be found on the surfaces of plants and animals. Pseudomonas bacteria are found in nature in a biofilm or in planktonic form. Pseudomonas bacteria are renowned for their metabolic versatility as they can grow under a variety of growth conditions and do not need any organic growth factors. This organism is an opportunistic human pathogen. While it rarely infects healthy individuals, immunocompromised patients, like burn victims, AIDS-, cancer- or cystic fibrosis-patients are at increased risk for infection with this environmentally versatile bacteria. It is an important soil bacterium with a complex metabolism capable of degrading polycyclic aromatic hydrocarbons, and producing interesting, biologically active secondary metabolites including quinolones, rhamnolipids, lectins, hydrogen cyanide, and phenazines. Production of these products is likely controlled by complex regulatory networks making Pseudomonas aeruginosa adaptable both to free-living and pathogenic lifestyles. The bacterium is naturally resistant to many antibiotics and disinfectants, which makes it a difficult pathogen to treat.