Query: NC_007426:205390 Natronomonas pharaonis DSM 2160, complete genome Lineage: Natronomonas pharaonis; Natronomonas; Halobacteriaceae; Halobacteriales; Euryarchaeota; Archaea General Information: Isolated from Lake Gabara in Egypt. Extreme haloalkaliphilic archeon. Natronomonas pharaonis is able to survive at high salt and pH conditions which results in limited nitrogen availability through ammonium. In order to compensate for this, Natronomonas pharaonis has developed three systems to promote nitrogen assimilation: direct uptake of ammonia, uptake of nitrate, and uptake of urea. Another problem with high pH environments is the use of a proton gradient for the generation of ATP, which other alkaliphiles have adapted to by substitution of sodium ions for protons. However, this organism utilizes protons for ATP generation as determined by experimental data.
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General Information: This strain has been developed for worldwide commercial use to control crown gall. This species is used commercially to control crown gall, a tumorogenic plant disease caused by the ubiquitous soil-borne pathogen Agrobacterium tumefaciens, which affects susceptible woody plants worldwide. The pathogen is responsible for nursery and orchard losses among stone fruit trees, grapes, apples, pears, nut trees, caneberries, clematis, hops, kiwifruit, persimmons, roses and many ornamental annuals, trees and shrubs. Infected plants are usually weakened and unproductive due to their damaged root system.