Query: NC_007404:387827 Thiobacillus denitrificans ATCC 25259, complete genome Lineage: Thiobacillus denitrificans; Thiobacillus; Hydrogenophilaceae; Hydrogenophilales; Proteobacteria; Bacteria General Information: This organism was originally isolated from soil from Texas, USA. Iron- and sulfur-oxidizing bacterium. This organism was isolated from a biofilm obtained from a municipal wastewater treatment facility. It has subsequently been found in soil, mud, both freshwater and marine sediment, and industrial wastewater. It is a member of the beta proteobacteria and an obligate chemolithoautotroph.
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General Information: This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Myxococcus fulvus produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.