Query: NC_007354:77108 Ehrlichia canis str. Jake, complete genome
Lineage: Ehrlichia canis; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.
Subject: NC_004842:1031020 Anaplasma marginale str. St. Maries, complete genome
Lineage: Anaplasma marginale; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain was recovered from an acutely infected cow from Northern Idaho, USA and bears an msp1a genotype of JBB. This strain is transmitted by ticks and is known to be virulent. This organism is the causative agent of bovine anaplasmosis and is an obligate intracellular pathogen. Transmission occurs via an arthropod vector (tick) and is a major problem in tropical regions where it causes severe morbidity in cattle populations. The bacterium lives intracellularly within membrane-bound vesicles in the host erythrocyte, a cell type which it specifically targets, resulting in severe anemia for the host organism.