Query: NC_007205:841818 Candidatus Pelagibacter ubique HTCC1062, complete genome Lineage: Pelagibacter ubique; Pelagibacter; Pelagibacteraceae; Rickettsiales; Proteobacteria; Bacteria General Information: They were originally named SAR11 and known only from their rRNA genes, which were first identified in environmental samples from the Sargasso Sea in 1990. P. ubique are possibly the most numerous bacteria in the world.
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General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.