Pre_GI: SWBIT SVG BLASTP

Query: NC_006512:2789098 Idiomarina loihiensis L2TR, complete genome

Lineage: Idiomarina loihiensis; Idiomarina; Idiomarinaceae; Alteromonadales; Proteobacteria; Bacteria

General Information: This is the type strain for this organism, which was isolated from a hydrothermal vent at a depth of 1300 m from the Lo'ihi Seamount southeast of Hawaii. This organism grows optimally in salt concentrations of 7.5 to 10%. Genome comparison has suggested that the bacterium has maintained its amino acid transport and degradation systems but lost sugar transport and certain sugar metabolic genes suggesting that it lives on amino acids rather than sugars. This may be in keeping with the environment this organism grows in, which is at hydrothermal deep sea vents that are characterized by collections of proteinaceous particles. This organism may colonize these particles by producing exopolysaccharides.

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BLASTP Alignment.txt

Subject: NC_007384:4095016 Shigella sonnei Ss046, complete genome

Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.