Query: NC_006363:36959 Nocardia farcinica IFM 10152 plasmid pNF2, complete sequence
Lineage: Nocardia farcinica; Nocardia; Nocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This type strain was isolated from the bronchus of a male Japanese patient. Opportunistic human pathogen. This genus was originally described from specimens isolated by plating soil suspensions on diagnostic sensitivity test plates augmented with antifungal agents. Organisms in this genus cause opportunistic human pulmonary and systemic nocardiosis. This can complicate existing debilitating conditions such as leukemia, lymphoma, or other neoplasms, or illnesses in patients with compromised immune systems.
Subject: NC_003384:109036 Salmonella enterica subsp. enterica serovar Typhi str. CT18 plasmid
Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This strain is a multidrug resistant strain of Salmonella typhi. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.