Query: NC_006350:595893 Burkholderia pseudomallei K96243 chromosome 1, complete sequence Lineage: Burkholderia pseudomallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: This strain was a clinical isolate from Thailand. The genome of this organism carries many genomic islands as compared to the related organism B. mallei, suggesting extensive horizontal transfer. Opportunistic pathogen. This species is an opportunistic pathogen and can cause pneumonia, bacteremia, and melioidosis. It is normally found in terrestrial environments and has been recovered from rice paddies and moist tropical soil. It is endemic in Asia and Australia, but can be found in other parts of the world. The organism can exist intracellularly and can spread through the bloodstream (bacteremia).
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General Information: This species is associated with infections in cystic fibrosis patients. It is an important opportunistic pathogen, colonizing the lungs and associated with a decrease in long-term survival. A minority of patients with this infection may also develop "cepacia syndrome", which leads to an acute clinical decline which is frequently fatal. This species is a member of the Burkholderia cepacia complex, although it does not appear to spread from patient to patient as do the other members of the group.