Query: NC_006348:2372945 Burkholderia mallei ATCC 23344 chromosome 1, complete sequence Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: This type strain came from a Chinese patient in Burma who had glanders in 1944. Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.
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General Information: Obligately chemolithoautotrophic, haloalkaliphilic, mesophilic, microaerophilic and sulfur-oxidizing bacterium. Uses CO2 as a carbon source and reduced inorganic sulfur compounds as an energy source. Utilizes ammonium and urea, but not nitrate or nitrite, as a N-source. Isolated from a full-scale Thiopaq bioreactor in the Netherlands used to remove H2S from biogas. Thioalkalivibrio species are commonly isolated from soda lakes and tend to dominate the microbial community of hypersaline soda lakes. These organisms have a pH optimum of 10 and are able to oxidize hydrogen sulfide to elemental sulfur. Thioalkalivibrio species have also been isolated from sulfide oxidizing bioreactors which remove sulfide from refinery and natural gas.