Pre_GI: SWBIT SVG BLASTP

Query: NC_006347:3638165 Bacteroides fragilis YCH46, complete genome

Lineage: Bacteroides fragilis; Bacteroides; Bacteroidaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism can become an opportunistic pathogen, infecting anywhere in the body and causing abcess formation. Enterotoxigenic Bacterioides fragilis (ETBF) is associated with diarrheal diseases. This strain was isolated from a patient with septicemia in Japan. Common gut bacterium. This group of microbes constitute the most abundant members of the intestinal microflora of mammals. Typically they are symbionts, but they can become opportunistic pathogens in the peritoneal (intra-abdominal) cavity. Breakdown of complex plant polysaccharides such as cellulose and hemicellulose and host-derived polysaccharides such as mucopolysaccharides is aided by the many enzymes these organisms produce. Although only a minor component of the human gut microflora, this organism is a major component of clinical specimens and is the most common anaerobe isolated.

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BLASTP Alignment.txt

Subject: NC_000117:845141 Chlamydia trachomatis D/UW-3/CX, complete genome

Lineage: Chlamydia trachomatis; Chlamydia; Chlamydiaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: Isolated from the cervix of an asymptomatic female. Opportunistic pathogen. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. This species causes infection that leads to blindness and sexually transmitted diseases in humans. There are 15 serovariants that preferentially cause disease in either the eye or the urogenital tract. The trachoma (infection of the mucous membrane of the eyelids) biovars are noninvasive and can cause blinding trachoma (variants A, B, Ba, and C), or sexually transmitted diseases (variants, D, E, F, G, H, I, J, and K). The lymphogranuloma venereum biovars (variants L1, L2, and L3) can cross the epithelial cells of mucous membranes and then travel through the lymphatic system where they multiply within mononuclear phagocytes found within the lymph nodes. This is a trachoma biovar, serovar D strain.