Query: NC_006347:2899653 Bacteroides fragilis YCH46, complete genome Lineage: Bacteroides fragilis; Bacteroides; Bacteroidaceae; Bacteroidales; Bacteroidetes; Bacteria General Information: This organism can become an opportunistic pathogen, infecting anywhere in the body and causing abcess formation. Enterotoxigenic Bacterioides fragilis (ETBF) is associated with diarrheal diseases. This strain was isolated from a patient with septicemia in Japan. Common gut bacterium. This group of microbes constitute the most abundant members of the intestinal microflora of mammals. Typically they are symbionts, but they can become opportunistic pathogens in the peritoneal (intra-abdominal) cavity. Breakdown of complex plant polysaccharides such as cellulose and hemicellulose and host-derived polysaccharides such as mucopolysaccharides is aided by the many enzymes these organisms produce. Although only a minor component of the human gut microflora, this organism is a major component of clinical specimens and is the most common anaerobe isolated.
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General Information: This strain can suppress the diseases caused by Rhizoctonia solani and Pythium ultimum which affect cotton plants. The production of a number of antibiotics (pyrrolnitrin, pyoluteorin, and 2,4-diacetylphloroglucinol) as well as the production of siderophores (which may affect the ability of competing organisms to obtain environmental iron) by this strain can inhibit phytopathogen growth such as the above-mentioned fungi. The genome of this organism contains a number of genes, estimated at 5.7 % of the chromosome, that encode proteins that are involved in secondary metabolism. A large number of repeat elements (REP) are also found in the genome in greater numbers than in related Pseudomonas spp.