Query: NC_006300:600516 Mannheimia succiniciproducens MBEL55E, complete genome Lineage: Mannheimia succiniciproducens; Mannheimia; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria General Information: This bacterium was isolated from a bovine rumen. Succinic acid producing bacterium. This bacterium is able to produce a large amount of succinic acid from readily available agricultural byproducts. Succinic acid is an important component in the manufacture of synthetic resins and biodegradable polymers. Mannheimia succiniciproducens can grow on media which includes whey, a byproduct of the cheese industry which is normally discarded, and corn steep liquor (CSL), which is a byproduct of corn starch production. The organism has been able to produce production-level amounts of succinic acid in both batch and continuous cultures in media containing these inexpensive components.
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General Information: This organism was discovered in 1819 by Bizio who named the organism after the Italian physicist Serrati. It was considered a nonpathogenic organism until late in the 20th century, although pathogenicity was noted as early as 1913. Serratia marcescens is an opportunistic human pathogen that is increasingly associated with life-threatening hospital-acquired infections. It is an environmental organism that has a broad host range, and is capable of infecting vertebrates and invertebrates, as well as plants. In humans, Serratia marcescens can cause meningitis (inflammation of the membrane surrounding the brain and spinal cord), endocarditis (inflammation of heart muscle) and pyelonephritis (inflammation of the kidneys). Many strains are resistant to multiple antibiotics. Environmental isolates are noted by production of the red pigment prodigiosin.