Pre_GI: SWBIT SVG BLASTP

Query: NC_006155:2084669 Yersinia pseudotuberculosis IP 32953, complete genome

Lineage: Yersinia pseudotuberculosis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a fully virulent serotype I strain isolated from a human patient. Environmental bacterium that causes gastrointestinal disease. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. This organism was first isolated in 1883 by Malassez and Vignal and is termed pseudotuberculosis since it causes lesions in the lung that are similar to those observed during tuberculosis infection. It is ubiquitous in the environment and is a food and waterborne pathogen that affects animals as well as humans by causing gastroenteritis like Yersinia enterocolitica.

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BLASTP Alignment.txt

Subject: NC_009009:219087 Streptococcus sanguinis SK36, complete genome

Lineage: Streptococcus sanguinis; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This strain was isolated from human dental plaque in 1980 and is virulent in a rat model. Indigenous oral bacteria that causes dental decay and possibly endocarditis. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This microbe is found associated with human oral bacterial communities and can colonize the dental surfaces, aiding other organisms in attachment. Progression of caries and periodontal disease are associated with this microbe as is endocarditis which can lead to death.