Query: NC_006142:33268 Rickettsia typhi str. Wilmington, complete genome Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.
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General Information: This strain was collected from the Sargasso Sea at a depth of 10 meters. Phototrophic bacterium. Organisms in this aerobic phototrophic genus are found in marine environments. Members of this group produce bacteriochlorophyll a, which is normally found in anaerobic organisms. One theory to explain this is that the anoxygenic photosynthetic gene cluster was acquired by these organisms via lateral gene transfer. Although they require an organic carbon substrate for growth, they are able to supplement a significant fraction of their metabolic requirements with photosynthetically derviced energy. This species was isolated from a marine cyanobacterial mat. Although they require an organic carbon substrate for growth, they are able to supplement a significant fraction of their metabolic requirements with photosynthetically derviced energy. The presence of the carotenoids bacteriorubixanthinal and erythroxanthin sulfate give this organism a reddish color.