Query: NC_006142:243899 Rickettsia typhi str. Wilmington, complete genome
Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.
Subject: NC_014974:404015 Thermus scotoductus SA-01 chromosome, complete genome
Lineage: Thermus scotoductus; Thermus; Thermaceae; Thermales; Deinococcus-Thermus; Bacteria
General Information: This is a thermophilic, facultatively mixotrophic sulfur-oxidizing bacterium. Thermus scotoductus SA-01 was isolated from fissure water in a South African gold mine. This organism is a thermophilic bacterium which was isolated from fissure water in the Witwatersrand Supergroup at a depth of 3.2 km below surface in a South African gold mine. It is a 2.9-billion-year-old formation of low permeability sandstone and shale with minor volcanic units and conglomerates. The ambient temperature of the rock is approximately 60°C. Samples were collected from a freshly mined rock surface and from a water-producing borehole that penetrated 121 m horizontally into the formation at a depth of 3,198 m. T. scotoductus SA-01 is a facultative anaerobe capable of coupling the oxidation of organic substrates to reduction of a wide range of electron acceptors, including nitrate, Fe(III), Mn(IV) or S(0) as terminal electron acceptors.