Query: NC_005955:947500 Bartonella quintana str. Toulouse, complete genome
Lineage: Bartonella quintana; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Bartonella quintana str. Toulouse was isolated from human blood in Toulouse, France in 1993. Causative agent of trench fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was first identified as the causative agent of louse-born trench fever during World War I. Up to 800 000 were infected in the trenches because of the louse insect vector that was widespread due to poor sanitation. The disease is now found associated with immunocompromized patients, especially HIV patients and homeless alcoholics.
Subject: NC_012416:4973 Wolbachia sp. wRi, complete genome
Lineage: Wolbachia; Wolbachia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Endosymbiont. Obligate intracellular bacterium infects around 20% of all insect species. Naturally infects Drosophila simulans and induces almost complete cytoplasmic incompatibility in its host. Wolbachia sp. subsp. Drosophila simulans (strain wRi) is an intracellular proteobacterium that infect insects as well as isopods, spiders, scorpions, mites, and filarial nematodes. It is maternally inherited and induces reproductive alterations of insect populations by male killing, feminization, parthenogenesis, or cytoplasmic incompatibility. In insect populations, Wolbachia sp. induce reproductive manipulations to enhance their own spreading. The most frequently observed reproductive abnormality is cytoplasmic incompatibility, where uninfected females are unable to produce offspring with infected males, whereas infected females can produce offspring with both infected and uninfected males, thus creating a reproductive advantage for infected females. Other spectacular effects of Wolbachia sp. infections are male embryo killing, feminization, and parthenogenesis induction.