Pre_GI: SWBIT SVG BLASTP

Query: NC_005861:544280 Candidatus Protochlamydia amoebophila UWE25, complete genome

Lineage: Protochlamydia amoebophila; Protochlamydia; Parachlamydiaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: An endosymbiont of free-living amoebae (Acanthamoeba sp. endosymbiont UWE25) and implicated as a potential human pathogen this strain is an environmental isolate. Amoeba endosymbiont. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. Candidatus Protochlamydia amoebophila, originally Parachlamydia is an endosymbiont of free-living amoebae (Acanthamoeba). This organism is an obligate intracellular endosymbiont and lives in small inclusions dispersed throughout the host cell.

Subject: NC_005955:947500 Bartonella quintana str. Toulouse, complete genome

Lineage: Bartonella quintana; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella quintana str. Toulouse was isolated from human blood in Toulouse, France in 1993. Causative agent of trench fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was first identified as the causative agent of louse-born trench fever during World War I. Up to 800 000 were infected in the trenches because of the louse insect vector that was widespread due to poor sanitation. The disease is now found associated with immunocompromized patients, especially HIV patients and homeless alcoholics.