Query: NC_005823:3454000 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 Lineage: Leptospira interrogans; Leptospira; Leptospiraceae; Spirochaetales; Spirochaetes; Bacteria General Information: This strain was isolated from a patient with severe leptospirosis during an epidemic in 1996. This organism is the causative agent of leptospirosis, a tropical zoonosis transmitted by direct contact with the urine of infected animals. This motile and obligately aerobic organism grows optimally at 28-30 C. Many serovars are adapted for specific mammalian reservoir hosts, which harbor the organisms in their renal tubules and shed them in their urine. Because of the large spectrum of animal species that serve as reservoirs, leptospirosis is considered to be the world's most widespread zoonotic disease.
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General Information: Rickettsia massiliae MTU5 was isolated from the tick Rhipicephalus turanicus collected from horses in Le Sambuc, Bouches-du Rhone, France. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia massiliae is a member of the spotted fever group of the Rickettsiales and has been isolated from ticks in Europe and Africa. Rickettsia massiliae does not appear to cause disease in humans.