Pre_GI: SWBIT SVG BLASTP

Query: NC_005362:550823 Lactobacillus johnsonii NCC 533, complete genome

Lineage: Lactobacillus johnsonii; Lactobacillus; Lactobacillaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This strain is a human isolate from the Nestle strain collection that has been studied for immunomodulation as well as pathogen inhibition. Probiotic microorganism. They are commonly found in the oral, vaginal, and intestinal regions of many animals. They are important industrial microbes that contribute to the production of cheese, yogurt, and other products such as fermented milks, all stemming from the production of lactic acid, which inhibits the growth of other organisms as well as lowering the pH of the food product. Industrial production requires the use of starter cultures, which are carefully cultivated, created, and maintained, which produce specific end products during fermentation that impart flavor to the final product, as well as contributing important metabolic reactions, such as the breakdown of milk proteins during cheese production. The end product of fermentation, lactic acid, is also being used as a starter molecule for complex organic molecule syntheses. Lactobacillus johnsonii is found in the human gut. It is a member of the acidophilus group of intestinal lactobacilli that has been extensively studied for their "probiotic" activities.

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BLASTP Alignment.txt

Subject: NC_002162:333303 Ureaplasma parvum serovar 3 str. ATCC 700970, complete genome

Lineage: Ureaplasma parvum; Ureaplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria

General Information: This organism (Ureaplasma urealyticum biovar 1) is normally found as a commensal organism in the human genital tract. As an opportunistic pathogen, it can cause a sexually-transmitted disease and is recognized as causing non-chlamydial non-gonococcal urethritis. It can also cause obstetric complications in pregnant women, severe infections in infants, as well as meningitis. Like other Mollicutes, it is a wall-less bacterium and has undergone marked genome reduction. This organism appears to generate ATP through the hydrolysis of urea by the urease enzyme.