Query: NC_005295:998000 Ehrlichia ruminantium str. Welgevonden, complete genome
Lineage: Ehrlichia ruminantium; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain was isolated in mice from an infected tick. Obligate intracellular bacterium and causative agent of heartwater. This organism causes heartwater, a disease with a high mortality rate that affects both wild and domesticated ruminants in sub-Saharan Africa and parts of the Caribbean. The name heartwater refers to the hydropericardium (excessive fluid in the sac surrounding the heart) commonly found associated with infection. This organism is found in membrane-bound vacuoles in endothelial cells and neutrophils and is an obligate intracellular parasite.
Subject: NC_006833:409599 Wolbachia endosymbiont strain TRS of Brugia malayi, complete
Lineage: Wolbachia endosymbiont of Brugia malayi; Wolbachia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: A nematode endosymbiont. This group of bacteria are associated with a variety of invertebrate species, some as pathogens, some in a symbiotic relationship. Typically these organisms are transmitted maternally from mother to daughter transovarially (through the egg) although these bacteria can affect their hosts reproductive capabilities in order to enhance transmission. The net outcome is the increase of hosts carrying the bacteria in the next generation, thereby increasing transmission. This strain naturally infects Brugia malayi, a parasitic filarial nematode that causes lymphatic filariasis, one of the most devastating diseases in humans. The endosymbiont plays important roles in the biology of the nematide host. One of the known such effects are aberrant sex ratios in the host, parthenogenesis and feminization of genetic males, etc.