Query: NC_005085:2869159 Chromobacterium violaceum ATCC 12472, complete genome
Lineage: Chromobacterium violaceum; Chromobacterium; Chromobacteriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: Chromobacterium violaceum ATCC 12472 was isolated from freshwater in Malaya. Common tropical soil bacterium. This facultative organism is an abundant environmental bacterium that lives in tropical and subtropical regions in the soil and water. It has exploitable properties including the ability to produce a bactericidal purple pigment, violacein, as well as the ability to produce a bioplastic and to biologically solubilize gold from the environment. It is occasionally pathogenic in immunocompromised individuals or children where it may cause diarrhea, but sometimes causes septicemia and is at times fatal.
Subject: NC_010120:2029880 Neisseria meningitidis 053442, complete genome
Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.