Query: NC_004663:4977635 Bacteroides thetaiotaomicron VPI-5482, complete genome
Lineage: Bacteroides thetaiotaomicron; Bacteroides; Bacteroidaceae; Bacteroidales; Bacteroidetes; Bacteria
General Information: This is the type strain for this organism and was isolated from the feces of a healthy adult. Common gastrointestinal bacterium. This group of microbes constitute the most abundant members of the intestinal microflora of mammals. Typically they are symbionts, but they can become opportunistic pathogens in the peritoneal (intra-abdominal) cavity. Breakdown of complex plant polysaccharides such as cellulose and hemicellulose and host-derived polysaccharides such as mucopolysaccharides is aided by the many enzymes these organisms produce. Bacteroides thetaiotaomicron is one of the two major Bacteroidesspecies found in the intestine. This organism has been used in studies on gut microflora composition and succession.
Subject: NC_006932:1596732 Brucella abortus biovar 1 str. 9-941 chromosome I, complete
Lineage: Brucella abortus; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.