Pre_GI: SWBIT SVG BLASTP

Query: NC_004310:1578918 Brucella suis 1330 chromosome I, complete sequence

Lineage: Brucella suis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: A swine isolate. Causes brucellosis, infectious abortions, fevers. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a swine-specific Brucella. It causes infectious abortions in animals and a systemic, febrile (feverish) illness in humans. Brucella suis is considered a potential bioterrorism agent and was the first pathogenic organism to be weaponized by the USA.

Subject: NC_012039:1399699 Campylobacter lari RM2100, complete genome

Lineage: Campylobacter lari; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Causes gastrointestinal disease. This organism is closely related to C. jejuni and C. coli and is a foodborne pathogen that causes gastroenteritis and diarrhea. In addition this organism can cause bacteremia and septicemia in immunocompromised individuals. The bacterium is found in a variety of habitats including water environments, and seagulls are considered a reservoir for the organism. Shellfish can harbor the organism when inhabiting water contaminated by seagulls carrying the organism.