Query: NC_003911:3453764 Silicibacter pomeroyi DSS-3, complete genome Lineage: Ruegeria pomeroyi; Ruegeria; Rhodobacteraceae; Rhodobacterales; Proteobacteria; Bacteria General Information: Formerly Silicibacter pomeroyi, his marine bacterium is a member of the Roseobacter clade and was isolated off of the coast of Georgia in 1998. Dimethylsulfoniopropionate-degrading bacterium. Capable of degrading the organic sulfur compound DMSP (dimethylsulfoniopropionate) and can metabolize a number of sulfur compounds. DMSP is synthesized by marine algae and the degradation product dimethylsulfide contributes to the global sulfur cycle.
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General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.