Query: NC_003902:2933121 Xanthomonas campestris pv. campestris str. ATCC 33913, complete Lineage: Xanthomonas campestris; Xanthomonas; Xanthomonadaceae; Xanthomonadales; Proteobacteria; Bacteria General Information: This strain was originally isolated from cabbage. Causes black rot disease in crucifers. This genus consists of plant-specific yellow-pigmented microbes, some of which are economically important phytopathogens that devastate crops such as citrus plants, rice, beans, grape, and cotton. These organisms are almost exclusively found associated with their plant hosts and are not found free in the soil. This species is a major cause of black rot in crucifers, a disease that results in massive tissue degeneration. It also produces an extracellular polysaccharide known as xanthan, which is harvested commercially as a food stabilizing agent for use in industry.
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General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.