Query: NC_003869:2143892 Thermoanaerobacter tengcongensis MB4, complete genome Lineage: Caldanaerobacter subterraneus; Caldanaerobacter; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria General Information: This organism was originally isolated from a hot spring in Tengcong, China, and is the type strain for the species. Genomic analysis indicates it is similar to Bacillus halodurans and that it has one of the most biased leading strand distribution of genes. Although the organism has not been observed to be motile or to sporulate, it does contain genes for both functions. The bacterium produces acetate and ethanol from glucose and cannot degrade xylan and cellulose.
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General Information: This strain (originally 5636/77) was isolated from a diarrheic patient in 1977 and minimally passaged. This organism is the leading cause of bacterial food poisoning (campylobacteriosis) in the world, and is more prevalent than Salmonella enteritis (salmonellosis). Found throughout nature, it can colonize the intestines of both mammals and birds, and transmission to humans occurs via contaminated food products. This organism can invade the epithelial layer by first attaching to epithelial cells, then penetrating through them. Systemic infections can also occur causing more severe illnesses.