Pre_GI: SWBIT SVG BLASTP

Query: NC_003454:249304 Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete

Lineage: Fusobacterium nucleatum; Fusobacterium; Fusobacteriaceae; Fusobacteriales; Fusobacteria; Bacteria

General Information: Normal oral and gastrointestinal bacterium. This genus contains mostly obligately anaerobic bacilli. Many of the isolates are spindle-shaped, or fusiform. This organism belongs to the normal microflora of the human oral and gastrointestinal tracts. It is a very long and slender spindle-shaped bacillus with sharply pointed ends that is characterized by the ability to invade soft tissues. It acts as a bridge between early and late colonizers of the tooth surface, and exerts synergism with other bacteria in mixed infections. It is most frequently associated with periodontal diseases, as well as with some invasive human infections of the head and neck, chest, lung, liver and abdomen, and some anginas. One of the major amino acid and sugar fermentation pathways in Fusobacterium nucleatum produces butyric and acetic acids.

Subject: NC_008346:1499963 Syntrophomonas wolfei subsp. wolfei str. Goettingen, complete

Lineage: Syntrophomonas wolfei; Syntrophomonas; Syntrophomonadaceae; Clostridiales; Firmicutes; Bacteria

General Information: Syntrophomonas wolfeisubsp. wolfei str. Goettingen (DSM 2245B) was isolated from anaerobic digestor sludge. Fatty acid-oxidizing bacterium. This organism is an anaerobic syntrophic fatty acid-oxidizing bacterium. It is the only bacterium known to produce energy from anaerobic degradation of saturated four to eight carbon fatty acids with protons serving as the electron acceptor. The cells have an unusual multilayered gram-negative cell wall. Syntrophomonas wolfei grows in coculture with Methanospirillum hungatei and can be isolated from anaerobic environments such as aquatic sediment or sewage digestor sludge.